Top 10 Ergonomic Mouse

Discover our curated selection of high-quality products.

Last update: 12-07-2026

Best Mice overall →
1
Logitech Lift Vertical Ergonomic Mouse, Wireless, Bluetooth or Logi Bolt USB receiver, Quiet clicks, 4 buttons, compatible with Windows/macOS/iPadOS, Laptop, PC - Graphite
Logitech

Logitech Lift Vertical Ergonomic Mouse, Wireless, Bluetooth or Logi Bolt USB receiver, Quiet clicks, 4 buttons, compatible with Windows/macOS/iPadOS, Laptop, PC - Graphite

  • Lift yourself up: When the desk life gets you down, lift yourself up with Logitech Lift Vertical Ergonomic Mouse - a great fit for small to medium right hands
  • Raise your hand into comfort: Rest on Lift upright mouse throughout the day, with a softly textured grip and snug thumb rest for level-above cosiness
  • 57 degrees of sooooothe: Lift’s vertical shape helps wrists feel like “ahhh” at work, and promotes a more natural posture in the forearm, for day-long comfort and productivity
  • Relax into focus: Settle into work with a cordless mouse featuring easy-to-reach customisable buttons, whisper-quiet clicks and a SmartWheel for smooth, seamless scrolling
  • Ergo-certified: Lift wireless vertical mouse has been designed, developed, tested and approved according to criteria set out by leading ergonomists
  • Connect your way: Connect via Bluetooth Low Energy or Logi Bolt USB to Windows, macOS, iPadOS, Chrome OS, or Linux, and enjoy up to 2 years battery life
  • Plastic parts in Lift include certified post consumer recycled plastic (Graphite: 70%, Off-White and Rose: 54%(6)). Certified carbon neutral
9.3/10
Editor's Pick
Available at Amazon
2
Anker® Ergonomic Optical USB Wired Vertical Mouse 1000 / 1600 DPI, 5 Buttons
Anker

Anker® Ergonomic Optical USB Wired Vertical Mouse 1000 / 1600 DPI, 5 Buttons

  • Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
  • 1000/1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
  • Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
  • 1.5m/4.9ft USB cable length, product dimensions: 120*62.8*74.8 mm; product weight: 5.3 oz.
  • Package includes: 1 Anker Vertical Ergonomic Optical Mouse (with 4.9 ft cable), 1 instruction manual. Includes 18 month warranty and lifetime technical support guarantee.
9.2/10
Available at Amazon
3
UGREEN Ergonomic Vertical Mouse, 2.4GHz Wireless or Bluetooth, 1000/1600/2000/4000DPI, 5 Buttons, Connects Up to 3 Mac/PC Computers, 75° Ergonomic Angle, Windows, MacOS, Linux, Chrome OS, Android
UGREEN

UGREEN Ergonomic Vertical Mouse, 2.4GHz Wireless or Bluetooth, 1000/1600/2000/4000DPI, 5 Buttons, Connects Up to 3 Mac/PC Computers, 75° Ergonomic Angle, Windows, MacOS, Linux, Chrome OS, Android

  • Dual Mode: This ergonomic mouse offers both Bluetooth and 2.4GHz connectivity, allowing you to connect one 2.4G device and two Bluetooth devices simultaneously.
  • 4000DPI Precision: With four DPI options (1000/1600/2000/4000), you can easily adjust the sensitivity to match your usage or screen resolution, ensuring precise control.
  • Connect to 3 Devices: Seamlessly connect this wireless ergonomic mouse to three computers at once. Each DPI mode has independent memory, allowing you to switch between devices without affecting your preferred settings.
  • Wide Compatibility: Compatible with a wide range of operating systems, including Windows 7/8.1/10/11, macOS 10.15 and above, iOS 13.4 and above, iPad OS 14.0 and above, Linux, Chrome OS, and Android 5.0, making it versatile for various devices.
  • Durable and Reliable: This vertical mouse offers a wireless range of up to 10m. It has undergone laboratory testing, with the left and right buttons rated for 5 million clicks and the middle button rated for 1 million clicks, ensuring long-lasting durability and stability.
9.1/10
Available at Amazon
4
Logitech MX Vertical Ergonomic Mouse, Multi-Device, Bluetooth or 2.4GHz Wireless with USB Unifying Receiver, 4000 DPI Optical Tracking, 4 Buttons, Fast Charging, Laptop/PC/Mac/iPad OS- Black
Logitech

Logitech MX Vertical Ergonomic Mouse, Multi-Device, Bluetooth or 2.4GHz Wireless with USB Unifying Receiver, 4000 DPI Optical Tracking, 4 Buttons, Fast Charging, Laptop/PC/Mac/iPad OS- Black

  • Natural handshake position : The Logitech MX Vertical's natural handshake position helps reduce muscular activity by 10 percent compared to a standard computer mouse - without any loss in overall performance
  • Improved wrist posture : This wired and wireless bluetooth mouse features a distinct 57 Degree vertical angle that reduces the pressure on your wrist; it also ensures your thumb is positioned comfortably on the thumb rest
  • User tested. Ergonomist approved : 88% of ergonomics professionals would recommend MX Vertical (Survey, Ergo Expo and IAE Florence 2018 attendees)
  • Advanced Optical Tracking : The 4 000 DPI high-precision optical mouse sensor results in 4x less hand movement (compared to cordless mouse 1 000 DPI) and reduces fatigue. The cursor speed switch instantly adjusts DPI speed and accuracy with the touch of a button
  • Easy-Switch and Flow-enabled : Connect to up to three Windows PCs, Macs, laptops and switch between them at the tap of a button or by simply moving the cursor from one screen to another with Logitech FLOW (Requires Logitech Options software)
  • Rechargeable battery with Quick-Charging : MX Vertical wireless ergonomic mouse stays powered for up to four months on a full charge – and gets up to three hours of use from a one-minute quick charge
  • Compatible with iPadOS 13.1 or later* via Bluetooth, in addition to Windows 8, Windows 10 or later, and macOS 10.13 or later. *On the iPad, pointing, clicking, and scrolling will be supported by enabling the “Assistive Touch” accessibility feature
  • Claim your complimentary 1-month Adobe Creative Cloud subscription or 2-month Adobe Photography Plan with purchase of the MX Vertical to create, make and do like never before.
  • Note : In case of Wireless mouse, the USB receiver will be provided inside or along with the mouse.Rechargeable Li-Po battery (240 mAh)
  • Improved wrist posture : This wired and wireless bluetooth mouse features a distinct 57 Degree vertical angle that reduces the pressure on your wrist; it also ensures your thumb is positioned comfortably on the thumb rest.Battery:Rechargeable Li-Po battery (240 mAh)
9.0/10
Available at Amazon
5
ECHTPower Vertical Ergonomic Mouse Wireless, Rechargeable 2.4G Optical USB Mouse for Laptop/Desktop/PC/Macbook with 1000/1600/2400/3200/4000/4800 DPI,6 Buttons(Wireless Mouse)
ECHTPower

ECHTPower Vertical Ergonomic Mouse Wireless, Rechargeable 2.4G Optical USB Mouse for Laptop/Desktop/PC/Macbook with 1000/1600/2400/3200/4000/4800 DPI,6 Buttons(Wireless Mouse)

  • ★【Unique Vertical Mouse】: The wireless vertical mouse is designed to fit your hand. Its unique vertical shape reduces the muscle tension of your arm and adapts perfectly to numerous shapes and sizes of hands. The textured rubber surface of the thumb support provides additional comfort.
  • ★【Long Battery Running Time with 6 Buttons】: The Ergonomic Mouse Wireless built-in 600 mAh rechargeable battery, easy to charge with the included micro USB charging cable. 3D scroll wheel, DPI buttons, left and right mouse button, forward and back button offers the more convenient way to browse the Internet.
  • ★【6 Adjustable DPI】: The 2.4G Ergo Mouse with 6 adjustable DPI value (points per inch) settings allow you to change the sensitivity of the mouse speed (1000/1600/2400/3200/4000/4800), so you can reduce the speed for tasks that guarantee precision (such as colour correction or image editing) or increase the speed faster for surfing.
  • ★【2.4 GHz wireless Technology】: The wireless mouse adopted advanced 2.4 GHz wireless technology, it can work stably and quickly within 10m distance without interference. Supports Plug and Play: Simply connect the included USB Nano receiver to the USB port of your computer, no additional driver is needed.
  • ★【Easy Installation】: The wireless mice is compatible with Windows 7, 8, 10, Windows XP, Vista, ME, 2000 and Mac OS, or latest system. Simply connect the included USB Nano receiver to the USB port of your computer, no additional driver is required.
8.9/10
Available at Amazon
6
Anker AK-UBA 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, Macbook - Black

Anker AK-UBA 2.4G Wireless Vertical Ergonomic Optical Mouse, 800 / 1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, Macbook - Black

  • Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
  • 800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
  • Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
  • Enters power saving mode (power is cut off completely) after 8 minutes idle, press right or left button for it to wake. Product dimensions: 120*62.8*74.8 mm; product weight: 3.4 oz.
  • Package includes: 1 Anker Wireless Vertical Ergonomic Optical Mouse (2 AAA batteries not included), 1 2.4G USB receiver (in the bottom of the mouse), 1 instruction manual. 18-month hassle-free warranty.
8.7/10
Available at Amazon
7
Amazon Basics Ergonomic wireless mouse for Laptop, 2.4 GHz with USB receiver, adjustable DPI - Black
Amazon Basics

Amazon Basics Ergonomic wireless mouse for Laptop, 2.4 GHz with USB receiver, adjustable DPI - Black

  • Compact wireless mouse with adjustable DPI to adapt its sensitivity (600, 1000, 1600, 2400, or 3600 DPI)
  • High performance laser sensor Works on most surfaces including glass Clickable metallic scroll wheel Next/return thumb buttons for easy navigation through web pages
  • 2.4 GHz wireless connection with a 10m range; with AES-128 encryption for added security; this mouse works with a small USB receiver that can stay plugged into your computer without disturbing other ports
  • Ergonomically shaped with rubberized sides for a comfortable fit. Compatible with Windows 7, 8, and 10 Works with 1 AA battery (included). Available colors black (clean)/purple (elegant)/red (daring)/silver (contemporary)
  • Measurements 10.4 x 7.4 x 3.8 cm
  • Note: The USB dongle is in the box, you should also put it in a safe place if you are not using
  • The mouse is for right hand
8.7/10
Bestseller
Available at Amazon
8
Trust Verto Wired Ergonomic Mouse, Vertical Mouse with LED Illumination, 1000-1600 DPI, 6 Buttons, for Right Hand Users, Computer Mouse for PC and Laptop - Black
Trust

Trust Verto Wired Ergonomic Mouse, Vertical Mouse with LED Illumination, 1000-1600 DPI, 6 Buttons, for Right Hand Users, Computer Mouse for PC and Laptop - Black

  • GOODBYE STRAIN – This ergonomic mouse is the vertical solution to strain and pain. Its ergonomic shape brings your arm and wrist into a natural 60° position to work effortlessly
  • FEEL BETTER – A lightweight design and shaped to fit all sizes of hands this mouse will feel like a relief. Its thumb rest and rubber coating further improve grip and comfort
  • ACCURATE CONTROL – Ergonomics don’t have to be boring; with this vertical mouse you can access a 1000/1600 DPI optical sensor and two thumb buttons for accurate and quick control
  • PLUG & PLAY – Connect the Verto wired mouse with the 1.5m USB cable and you can start working instantly. The blue LED light will illuminate your mouse
  • LIGHT UP YOUR DAY – The stylish - yet subtle - light on the left side of the mouse adds a bit of flair to your workday
  • CHEERS FOR 5 YEARS – Enjoy worry-free use with our 5-year warranty; built to last and backed by our commitment to quality, you can enjoy your products with extra peace of mind
8.7/10
Available at Amazon
9
Trust Verto Wireless Ergonomic Mouse, Vertical Mouse with Storable USB Micro-receiver, 800-1600 DPI, 6 Buttons, Illuminated Mouse for Right Hand Users for PC, Laptop, Mac, Batteries Included - Black
Trust

Trust Verto Wireless Ergonomic Mouse, Vertical Mouse with Storable USB Micro-receiver, 800-1600 DPI, 6 Buttons, Illuminated Mouse for Right Hand Users for PC, Laptop, Mac, Batteries Included - Black

  • GOODBYE STRAIN – This ergonomic mouse is the vertical solution to strain and pain. Its ergonomic shape brings your arm and wrist into a natural 60° position to work effortlessly
  • FEEL BETTER – A lightweight design and shaped to fit all sizes of hands, this wireless mouse will feel like a relief. Its thumb rest and rubber coating further improve grip and comfort
  • WIRELESS FREEDOM – Don’t let cables influence your working position. The 10 meter wireless range of the Verto mouse is optimal freedom and better posture
  • ACCURATE CONTROL – Ergonomics don’t have to be boring. With this PC mouse you can access a 800/1200/1600 dpi optical sensor and two thumb buttons for accurate and quick control
  • PLUG & PLAY – Connect the micro-receiver of the Verto vertical mouse with your PC or laptop and you can start working instantly. Store the receiver in the special compartment when work is done
  • CHEERS FOR 5 YEARS – Enjoy worry-free use with our 5-year warranty; built to last and backed by our commitment to quality, you can enjoy your products with extra peace of mind
8.6/10
Available at Amazon
10
Logitech MX Master 2S Bluetooth Edition Wireless Mouse, Multi-Surface, Hyper-Fast Scrolling, Ergonomic, Rechargeable, Connects Up to 3 Mac/PC Computers - Graphite
Logitech

Logitech MX Master 2S Bluetooth Edition Wireless Mouse, Multi-Surface, Hyper-Fast Scrolling, Ergonomic, Rechargeable, Connects Up to 3 Mac/PC Computers - Graphite

  • Connect up to 3 Computers: Logitech Flow allows you to seamlessly control up to three computers with one wireless mouse, and copy-paste text, images and files between them (1)
  • Precise Control: This multi surface mouse uses Darkfield High Precision tracking to give you flawless control virtually anywhere – even on glass (2) with up to 4,000 DPI
  • Quickly Charges: Connect the Bluetooth mouse to your computer and get enough power for a full day of use in only 3 minutes; a full charge lasts up to 70 days (3)
  • Speed-Adaptive, Side-to-Side Scrolling: Scroll through web pages faster and easier with the speed-adaptive scroll wheel and side-to-side scrolling with a stroke of your thumb (4)
  • Finely Designed: An ergonomic wireless mouse with a hand-sculpted shape (5) that supports your hand and wrist, plus fine-motion control and well-positioned buttons and wheels
8.4/10
Available at Amazon

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